Anti-PMPCB Antibody (CAB12549)
- SKU:
- CAB12549
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PMPCB Antibody |
| 抗体コード: | CAB12549 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-380 of human PMPCB (NP_004270.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, HT-1080, Mouse kidney, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-380 of human PMPCB (NP_004270.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GTKK RSQL DLEL EIEN MGAH LNAY TSRE QTVY YAKA FSKD LPRA VEIL ADII QNST LGEA EIER ERGV ILRE MQEV ETNL QEVV FDYL HATA YQNT ALGR TILG PTEN IKSI SRKD LVDY ITTH YKGP RIVL AAAG GVSH DELL DLAK FHFG DSLC THKG EIPA LPPC KFTG SEIR VRDD KMPL AHLA IAVE AVGW AHPD TICL MVAN TLIG NWDR SFGG GMNL SSKL AQLT CHGN LCHS FQSF NTSY TDTG LWGL YMVC ESST VADM LHV |
| 遺伝子ID: | 9512 |
| Uniprot: | O75439 |
| セルラーロケーション: | Mitochondrion matrix |
| 計算された分子量: | 54kDa |
| 観察された分子量: | 54kDa |
| 同義語: | PMPCB, Beta-MPP, MPP11, MPPB, MPPP52, P-52 |
| バックグラウンド: | This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. |
| UniProt Protein Function: | PMPCB: Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Protease; EC 3.4.24.64 Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: mitochondrial matrix; mitochondrial inner membrane Molecular Function:metal ion binding; metalloendopeptidase activity Biological Process: cellular protein metabolic process; proteolysis; protein targeting to mitochondrion |
| NCBI Summary: | This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75439 |
| NCBI GenInfo Identifier: | 29840827 |
| NCBI Gene ID: | 9512 |
| NCBI Accession: | O75439.2 |
| UniProt Secondary Accession: | O75439,O60416, Q96FV4, |
| UniProt Related Accession: | O75439 |
| Molecular Weight: | 489 |
| NCBI Full Name: | Mitochondrial-processing peptidase subunit beta |
| NCBI Synonym Full Names: | peptidase (mitochondrial processing) beta |
| NCBI Official Symbol: | PMPCB |
| NCBI Official Synonym Symbols: | MPPB; P-52; MPP11; MPPP52; Beta-MPP |
| NCBI Protein Information: | mitochondrial-processing peptidase subunit beta; mitochondrial processing peptidase beta subunit |
| UniProt Protein Name: | Mitochondrial-processing peptidase subunit beta |
| UniProt Synonym Protein Names: | Beta-MPP; P-52 |
| UniProt Gene Name: | PMPCB |
| UniProt Entry Name: | MPPB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PMPCB antibody (CAB12549) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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