UniProt Protein Function: | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. |
NCBI Summary: | This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence. [provided by RefSeq, Dec 2010] |
UniProt Code: | Q6P1K2 |
NCBI GenInfo Identifier: | 114152119 |
NCBI Gene ID: | 100527963 |
NCBI Accession: | Q6P1K2.2 |
UniProt Secondary Accession: | Q6P1K2,Q5TCJ8, Q5TCJ9, Q5TCK0, Q5TCK1, Q5TCK3, Q69YZ9 Q6PHR4, Q6ZVE6, Q86VJ6, Q8N4T6, A8K0C5, |
Molecular Weight: | 20,230 Da |
NCBI Full Name: | Polyamine-modulated factor 1 |
NCBI Synonym Full Names: | PMF1-BGLAP readthrough |
NCBI Official Symbol: | PMF1-BGLAP |
NCBI Official Synonym Symbols: | PMF1 |
NCBI Protein Information: | PMF1-BGLAP protein |
UniProt Protein Name: | Polyamine-modulated factor 1 |
Protein Family: | Polyamine-modulated factor |
UniProt Gene Name: | PMF1 |
UniProt Entry Name: | PMF1_HUMAN |