Anti-PLSCR4 Antibody (CAB14670)
- SKU:
- CAB14670
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PLSCR4 Antibody |
| 抗体コード: | CAB14670 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-549, 22Rv1 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PLSCR4 (NP_065086.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSGV VPTA PEQP AGEM ENQT KPPD PRPD APPE YNSH FLPG PPGT AVPP PTGY PGGL PMGY YSPQ QPST FPLY QPVG GIHP VRYQ PGKY PMPN QSVP ITWM PGPT PMAN CPPG LEYL VQLD NIHV LQHF EPLE MMTC FETN NRYD IKNN SDQM VYIV TEDT DDFT RNAY RTLR PFVL RVTD CMGR EIMT MQRP FRCT CCCF CCPS ARQE LEVQ CPPG VTIG FVAE HWNL CRAV YSIQ NEKK ENVM RVRG PCST YGCG SDSV FEVK SLDG IS |
| 遺伝子ID: | 57088 |
| Uniprot: | Q9NRQ2 |
| セルラーロケーション: | Membrane, Single-pass type II membrane protein |
| 計算された分子量: | 24kDa/37kDa |
| 観察された分子量: | 37kDa |
| 同義語: | PLSCR4, TRA1 |
| バックグラウンド: |
| UniProt Protein Function: | PLSCR4: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 3q24 Cellular Component: plasma membrane; integral to membrane Molecular Function:phospholipid scramblase activity; protein binding; enzyme binding; calcium ion binding; CD4 receptor binding; SH3 domain binding Biological Process: phospholipid scrambling |
| UniProt Code: | Q9NRQ2 |
| NCBI GenInfo Identifier: | 212276457 |
| NCBI Gene ID: | 57088 |
| NCBI Accession: | Q9NRQ2.2 |
| UniProt Secondary Accession: | Q9NRQ2,Q2TTR3, Q658L3, Q6ZR73, Q7Z505, A8K2E9, |
| UniProt Related Accession: | Q9NRQ2 |
| Molecular Weight: | 24,797 Da |
| NCBI Full Name: | Phospholipid scramblase 4 |
| NCBI Synonym Full Names: | phospholipid scramblase 4 |
| NCBI Official Symbol: | PLSCR4 |
| NCBI Official Synonym Symbols: | TRA1 |
| NCBI Protein Information: | phospholipid scramblase 4; PL scramblase 4; cell growth inhibiting protein 43; Ca(2+)-dependent phospholipid scramblase 4 |
| UniProt Protein Name: | Phospholipid scramblase 4 |
| UniProt Synonym Protein Names: | Ca(2+)-dependent phospholipid scramblase 4; Cell growth-inhibiting gene 43 protein; TRA1 |
| Protein Family: | Phospholipid scramblase |
| UniProt Gene Name: | PLSCR4 |
| UniProt Entry Name: | PLS4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PLSCR4 antibody (CAB14670) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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