Anti-PLS3 Antibody (CAB3627)
- SKU:
- CAB3627
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-PLS3 Antibody |
抗体コード: | CAB3627 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IP |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PLS3 (NP_005023.2). |
申し込み: | WB IHC IP |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, MCF-7, BT-474, A-431, HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PLS3 (NP_005023.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDEM ATTQ ISKD ELDE LKEA FAKV DLNS NGFI CDYE LHEL FKEA NMPL PGYK VREI IQKL MLDG DRNK DGKI SFDE FVYI FQEV KSSD IAKT FRKA INRK EGIC ALGG TSEL SSEG TQHS YSEE EKYA FVNW INKA LEND PDCR HVIP MNPN TDDL FKAV GDGI VLCK MINL SVPD TIDE RAIN KKKL TPFI IQEN LNLA LNSA SAIG CHVV NIGA EDLR AGKP HLVL GLLW QIIK IGLF |
遺伝子ID: | 5358 |
Uniprot: | P13797 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 65kDa/69kDa/70kDa |
観察された分子量: | 71kDa |
同義語: | PLS3, BMND18, T-plastin, plastin-3 |
バックグラウンド: | Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants. |
UniProt Protein Function: | PLS3: Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: Xq23 Cellular Component: cytoplasm Molecular Function:calcium ion binding; actin binding Disease: Bone Mineral Density Quantitative Trait Locus 18 |
UniProt Code: | P13797 |
NCBI GenInfo Identifier: | 226694201 |
NCBI Gene ID: | |
NCBI Accession: | P13797.4 |
Molecular Weight: | ~ 71kDa |
NCBI Full Name: | Plastin-3 |
UniProt Protein Name: | Plastin-3 |
UniProt Synonym Protein Names: | T-plastin |
Protein Family: | Plastin |
UniProt Gene Name: | PLS3 |
UniProt Entry Name: | PLST_HUMAN |
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