Anti-PLRG1 Antibody (CAB9946)
- SKU:
- CAB9946
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-PLRG1 Antibody |
| 抗体コード: | CAB9946 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PLRG1 (NP_001188493.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PLRG1 (NP_001188493.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MVEE VQKH SVHT LVFR SLKR THDM FVAD NGKP VPLD EESH KRKM AIKL RNEY GPVL HMPT SKEN LKEK GPQN ATDS YVHK QYPA NQGQ EVEY FVAG VALT ADTK IQRM PSES AAQS LAVA LPLQ TKAD ANRT APSG SEYR HPGA SDRP QPTA MNSI VMET GNTK NSAL MAKK APTM PKPQ WHPP WKLY RV |
| 遺伝子ID: | 5356 |
| Uniprot: | O43660 |
| セルラーロケーション: | Nucleus, Nucleus speckle |
| 計算された分子量: | 56kDa/57kDa |
| 観察された分子量: | 57kDa |
| 同義語: | PLRG1, Cwc1, PRL1, PRP46, PRPF46, TANGO4 |
| バックグラウンド: | This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | PLRG1: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Belongs to the WD repeat PRL1/PRL2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 4q31.2-q32.1 Cellular Component: DNA replication factor A complex; nuclear membrane; nucleolus; nucleoplasm; nucleus Molecular Function:protein binding Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | O43660 |
| NCBI GenInfo Identifier: | 38257903 |
| NCBI Gene ID: | 5356 |
| NCBI Accession: | O43660.1 |
| UniProt Secondary Accession: | O43660,Q3KQY5, Q8WUD8, B3KMK4, |
| UniProt Related Accession: | O43660 |
| Molecular Weight: | 56,290 Da |
| NCBI Full Name: | Pleiotropic regulator 1 |
| NCBI Synonym Full Names: | pleiotropic regulator 1 |
| NCBI Official Symbol: | PLRG1 |
| NCBI Official Synonym Symbols: | Cwc1; PRL1; PRP46; PRPF46; TANGO4 |
| NCBI Protein Information: | pleiotropic regulator 1 |
| UniProt Protein Name: | Pleiotropic regulator 1 |
| Protein Family: | Pleiotropic regulator |
| UniProt Gene Name: | PLRG1 |
| UniProt Entry Name: | PLRG1_HUMAN |
 | Western blot analysis of extracts of mouse thymus, using PLRG1 antibody (CAB9946) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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