Anti-PLIN2 Antibody (CAB6276)
- SKU:
- CAB6276
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PLIN2 Antibody |
| 抗体コード: | CAB6276 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 168-437 of human PLIN2 (NP_001113.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, NIH/3T3, Mouse brain, Rat heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 168-437 of human PLIN2 (NP_001113.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MMQL VSSG VENA LTKS ELLV EQYL PLTE EELE KEAK KVEG FDLV QKPS YYVR LGSL STKL HSRA YQQA LSRV KEAK QKSQ QTIS QLHS TVHL IEFA RKNV YSAN QKIQ DAQD KLYL SWVE WKRS IGYD DTDE SHCA EHIE SRTL AIAR NLTQ QLQT TCHT LLSN IQGV PQNI QDQA KHMG VMAG DIYS VFRN AASF KEVS DSLL TSSK GQLQ KMKE SLDD VMDY LVNN TPLN WLVG PFYP QLTE SQNA QDQG AEMD KSSQ ETQR SEHK TH |
| 遺伝子ID: | 123 |
| Uniprot: | Q99541 |
| セルラーロケーション: | Membrane, Peripheral membrane protein |
| 計算された分子量: | 48kDa |
| 観察された分子量: | 48kDa |
| 同義語: | PLIN2, ADFP, ADRP |
| バックグラウンド: | The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | perilipin 2: May be involved in development and maintenance of adipose tissue. Belongs to the perilipin family. |
| UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 9p22.1 Cellular Component: endoplasmic reticulum; extracellular region; plasma membrane; lipid particle; nucleus; cytosol Biological Process: long-chain fatty acid transport; response to drug; sequestering of lipid; cellular lipid metabolic process; response to organic cyclic substance |
| NCBI Summary: | The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | Q99541 |
| NCBI GenInfo Identifier: | 34577059 |
| NCBI Gene ID: | 123 |
| NCBI Accession: | NP_001113.2 |
| UniProt Secondary Accession: | Q99541,Q9BSC3, |
| UniProt Related Accession: | Q99541 |
| Molecular Weight: | 48,075 Da |
| NCBI Full Name: | perilipin-2 |
| NCBI Synonym Full Names: | perilipin 2 |
| NCBI Official Symbol: | PLIN2 |
| NCBI Official Synonym Symbols: | ADFP; ADRP |
| NCBI Protein Information: | perilipin-2; adipophilin; adipose differentiation-related protein |
| UniProt Protein Name: | Perilipin-2 |
| UniProt Synonym Protein Names: | Adipophilin; Adipose differentiation-related protein; ADRP |
| UniProt Gene Name: | PLIN2 |
| UniProt Entry Name: | PLIN2_HUMAN |
 | Western blot analysis of extracts of HepG2 cells, using PLIN2 antibody (CAB6276) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Western blot analysis of extracts of various cell lines, using PLIN2 antibody (CAB6276) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Western blot analysis of extracts of Rat heart, using PLIN2 antibody (CAB6276) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat liver using PLIN2 Rabbit pAb (CAB6276) at dilution of 1:50 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human liver using PLIN2 Rabbit pAb (CAB6276) at dilution of 1:50 (40x lens). |
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