Anti-PLA2R1 Antibody (CAB10068)
- SKU:
- CAB10068
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PLA2R1 Antibody |
| 抗体コード: | CAB10068 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, SH-SY5Y, Mouse liver, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 870-1130 of human PLA2R1 (NP_031392.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GASW WIGL QEER ANDE FRWR DGTP VIYQ NWDT GRER TVNN QSQR CGFI SSIT GLWG SEEC SVSM PSIC KRKK VWLI EKKK DTPK QHGT CPKG WLYF NYKC LLLN IPKD PSSW KNWT HAQH FCAE EGGT LVAI ESEV EQAF ITMN LFGQ TTSV WIGL QNDD YETW LNGK PVVY SNWS PFDI INIP SHNT TEVQ KHIP LCAL LSSN PNFH FTGK WYFE DCGK EGYG FVCE KMQD TSGH GVNT SDMY PMPN TLEY GNRT YKII N |
| 遺伝子ID: | 22925 |
| Uniprot: | Q13018 |
| セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
| 計算された分子量: | 152kDa/168kDa |
| 観察された分子量: | 169kDa |
| 同義語: | CLEC13C, PLA2-R, PLA2G1R, PLA2IR, PLA2R, PLA2R1 |
| バックグラウンド: | This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| NCBI Summary: | This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010] |
| UniProt Code: | Q13018 |
| NCBI GenInfo Identifier: | 691753 |
| NCBI Gene ID: | 22925 |
| NCBI Accession: | |
| UniProt Related Accession: | Q13018 |
| Molecular Weight: | |
| NCBI Full Name: | phospholipase A2 receptor, partial |
| NCBI Synonym Full Names: | phospholipase A2 receptor 1 |
| NCBI Official Symbol: | PLA2R1 |
| NCBI Official Synonym Symbols: | PLA2R; PLA2-R; PLA2IR; CLEC13C; PLA2G1R |
| NCBI Protein Information: | secretory phospholipase A2 receptor |
| UniProt Protein Name: | |
| UniProt Gene Name: |
 | Western blot analysis of extracts of various cell lines, using PLA2R1 antibody (CAB10068) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat liver using PLA2R1 antibody (CAB10068) at dilution of 1:100 (40x lens). |
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