Anti-PIP5K1C Antibody (CAB17664)
- SKU:
- CAB17664
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-PIP5K1C Antibody |
| 抗体コード: | CAB17664 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of Human PIP5K1C. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide of Human PIP5K1C. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 23396 |
| Uniprot: | O60331 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | LCCS3, PIP5K-GAMMA, PIP5K1-gamma, PIP5Kgamma, PIP5K1C |
| バックグラウンド: | This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4, 5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010] |
| UniProt Protein Function: | PIP5K1C: a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 2.7.1.68; Carbohydrate Metabolism - inositol phosphate; Kinase, lipid Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytosol; focal adhesion; uropod Molecular Function:1-phosphatidylinositol-4-phosphate 5-kinase activity; protein binding Biological Process: actin cytoskeleton organization and biogenesis; cell-cell adhesion; neutrophil chemotaxis; phagocytosis; phosphatidylinositol biosynthetic process; regulation of phosphoinositide 3-kinase cascade; synaptic vesicle endocytosis; synaptic vesicle exocytosis Disease: Lethal Congenital Contracture Syndrome 3 |
| NCBI Summary: | This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010] |
| UniProt Code: | O60331 |
| NCBI GenInfo Identifier: | 78099088 |
| NCBI Gene ID: | 23396 |
| NCBI Accession: | O60331.2 |
| UniProt Secondary Accession: | O60331,Q7LE07, B7Z9E7, C6GIJ7, C6GIJ8, |
| UniProt Related Accession: | O60331 |
| Molecular Weight: | 70,214 Da |
| NCBI Full Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
| NCBI Synonym Full Names: | phosphatidylinositol-4-phosphate 5-kinase type 1 gamma |
| NCBI Official Symbol: | PIP5K1C |
| NCBI Official Synonym Symbols: | LCCS3; PIP5Kgamma; PIP5K-GAMMA; PIP5K1-gamma |
| NCBI Protein Information: | phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
| UniProt Protein Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma |
| UniProt Synonym Protein Names: | Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma |
| Protein Family: | Phosphatidylinositol 4-phosphate 5-kinase |
| UniProt Gene Name: | PIP5K1C |
| UniProt Entry Name: | PI51C_HUMAN |