Anti-PINX1 Antibody (CAB17172)
- SKU:
- CAB17172
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-PINX1 Antibody |
| 抗体コード: | CAB17172 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 127-328 of human PINX1 (NP_060354.4). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, Jurkat, HepG2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 127-328 of human PINX1 (NP_060354.4). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MKFT KGKD LSSR SKTD LDCI FGKR QSKK TPEG DASP STPE ENET TTTS AFTI QEYF AKRM AALK NKPQ VPVP GSDI SETQ VERK RGKK RNKE ATGK DVES YLQP KAKR HTEG KPER AEAQ ERVA KKKS APAE EQLR GPCW DQSS KASA QDAG DHVQ PPEG RDFT LKPK KRRG KKKL QKPV EIAE DATL EETL VKKK KKKD SK |
| 遺伝子ID: | 54984 |
| Uniprot: | Q96BK5 |
| セルラーロケーション: | |
| 計算された分子量: | 19kDa/37kDa |
| 観察された分子量: | 43kDa |
 | Western blot - PINX1 Polyclonal Antibody (CAB17172) |
| 同義語: | PINX1, LPTL, LPTS |
| バックグラウンド: |
| UniProt Protein Function: | PINX1: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. Belongs to the PINX1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; Tumor suppressor; Inhibitor Chromosomal Location of Human Ortholog: 8p23 Cellular Component: cytoplasm; intracellular membrane-bound organelle; kinetochore; mitochondrion; nuclear chromosome; nuclear chromosome, telomeric region; nucleolus; nucleus; spindle Molecular Function:protein binding Biological Process: mitotic metaphase plate congression; negative regulation of cell proliferation; negative regulation of protein ubiquitination; negative regulation of telomerase activity; negative regulation of telomere maintenance via telomerase; regulation of protein stability; regulation of telomerase activity; telomere maintenance via telomerase |
| UniProt Code: | Q96BK5 |
| NCBI GenInfo Identifier: | 547234890 |
| NCBI Gene ID: | 54984 |
| NCBI Accession: | NP_001271285.1 |
| UniProt Secondary Accession: | Q96BK5,Q548A5, Q6QWG9, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2 B2R9B1, |
| UniProt Related Accession: | Q96BK5 |
| Molecular Weight: | 19,714 Da |
| NCBI Full Name: | PIN2/TERF1-interacting telomerase inhibitor 1 isoform 2 |
| NCBI Synonym Full Names: | PIN2/TERF1 interacting, telomerase inhibitor 1 |
| NCBI Official Symbol: | PINX1 |
| NCBI Official Synonym Symbols: | LPTL; LPTS |
| NCBI Protein Information: | PIN2/TERF1-interacting telomerase inhibitor 1 |
| UniProt Protein Name: | PIN2/TERF1-interacting telomerase inhibitor 1 |
| UniProt Synonym Protein Names: | Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1 |
| Protein Family: | PIN2/TERF1-interacting telomerase inhibitor |
| UniProt Gene Name: | PINX1 |
| UniProt Entry Name: | PINX1_HUMAN |