Anti-PIGO Antibody (CAB18670)
- SKU:
- CAB18670
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-PIGO Antibody |
| 抗体コード: | CAB18670 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human PIGO. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, 22Rv1, Mouse uterus, Mouse spleen |
| 免疫原: | Recombinant protein of human PIGO. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 84720 |
| Uniprot: | Q8TEQ8 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| 計算された分子量: | 73kDa/118kDa |
| 観察された分子量: | 119kDa |
 | Western blot - PIGO Rabbit pAb (CAB18670) |
| 同義語: | PIGO, HPMRS2, GPI ethanolamine phosphate transferase 3 |
| バックグラウンド: | This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. |
| UniProt Protein Function: | PIGO: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Transferase; Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral; EC 2.-.-.- Chromosomal Location of Human Ortholog: 9p13.3 Cellular Component: endoplasmic reticulum membrane; membrane Molecular Function:mannose-ethanolamine phosphotransferase activity Biological Process: GPI anchor biosynthetic process Disease: Hyperphosphatasia With Mental Retardation Syndrome 2 |
| NCBI Summary: | This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | Q8TEQ8 |
| NCBI GenInfo Identifier: | 61252289 |
| NCBI Gene ID: | 84720 |
| NCBI Accession: | Q8TEQ8.3 |
| UniProt Secondary Accession: | Q8TEQ8,Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0 B1AML3, |
| UniProt Related Accession: | Q8TEQ8 |
| Molecular Weight: | 73,992 Da |
| NCBI Full Name: | GPI ethanolamine phosphate transferase 3 |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class O |
| NCBI Official Symbol: | PIGO |
| NCBI Official Synonym Symbols: | HPMRS2 |
| NCBI Protein Information: | GPI ethanolamine phosphate transferase 3 |
| UniProt Protein Name: | GPI ethanolamine phosphate transferase 3 |
| UniProt Synonym Protein Names: | Phosphatidylinositol-glycan biosynthesis class O protein; PIG-O |
| UniProt Gene Name: | PIGO |
| UniProt Entry Name: | PIGO_HUMAN |