| UniProt Protein Function: | Transcription activator. Regulates negatively chlorophyll biosynthesis and seed germination in the dark, and lightinduced degradation of PIF1 relieves this negative regulation to promote photomorphogenesis. Binds to the G-box motif (5'-CACGTG-3') found in many light-regulated promoters. Promotes the expression of SOM, and thus modulates responses to abscisic acid (ABA) and gibberellic acid (GA). |
| NCBI Summary: | Encodes a novel Myc-related bHLH transcription factor that has transcriptional activation activity in the dark. It is a key negative regulator of phytochrome-mediated seed germination and acts by inhibiting chlorophyll biosynthesis, light-mediated suppression of hypocotyl elongation and far-red light-mediated suppression of seed germination, and promoting negative gravitropism in hypocotyls. Light reduces this activity in a phy-dependent manner. The protein preferentially interacts with the Pfr forms of Phytochrome A (PhyA) and Phytochrome B (PhyB), is physically associated with APRR1/TOC1 and is degraded in red (R) and far-red (FR) light through the ubiquitin (ub)-26S proteasome pathway to optimize photomorphogenic development in Arabidopsis. It also negatively regulates GA3 oxidase expression. |
| UniProt Code: | Q8GZM7 |
| NCBI GenInfo Identifier: | 334184322 |
| NCBI Gene ID: | 816538 |
| NCBI Accession: | NP_001189559.1 |
| UniProt Secondary Accession: | Q8GZM7,Q0WQ83, Q3EBY0, Q9SL63, |
| UniProt Related Accession: | Q8GZM7 |
| Molecular Weight: | 44,715 Da |
| NCBI Full Name: | phytochrome interacting factor 3-like 5 |
| NCBI Official Symbol: | PIL5 |
| NCBI Official Synonym Symbols: | PHY-INTERACTING FACTOR 1; phytochrome interacting factor 3-like 5; PIF1; T2G17.2; T2G17_2 |
| NCBI Protein Information: | phytochrome interacting factor 3-like 5 |
| UniProt Protein Name: | Transcription factor PIF1 |
| UniProt Synonym Protein Names: | Basic helix-loop-helix protein 15; AtbHLH15; bHLH 15; Protein PHY-INTERACTING FACTOR 1; Protein PHYTOCHROME INTERACTING FACTOR 3-LIKE 5; Transcription factor EN 101; bHLH transcription factor bHLH015 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | PIF1 |
