Anti-Phospho-Jun-S63 Antibody (CABP0048)
- SKU:
- CABP0048
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-Phospho-Jun-S63 Antibody |
抗体コード: | CABP0048 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic phosphorylated peptide around S63 of human c-Jun (NP_002219.1). |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Rat |
ポジティブサンプル: | 293 |
免疫原: | A synthetic phosphorylated peptide around S63 of human c-Jun (NP_002219.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LTSP D |
遺伝子ID: | 3725 |
Uniprot: | P05412 |
セルラーロケーション: | Nucleus |
計算された分子量: | 35kDa |
観察された分子量: | 48kDa |
同義語: | AP-1, AP1, c-Jun, JUN, c |
バックグラウンド: | This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. |
UniProt Protein Function: | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306). |
NCBI Summary: | This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008] |
UniProt Code: | P05412 |
NCBI GenInfo Identifier: | 135298 |
NCBI Gene ID: | 3725 |
NCBI Accession: | P05412.2 |
UniProt Secondary Accession: | P05412,Q6FHM7, Q96G93, |
UniProt Related Accession: | P05412 |
Molecular Weight: | |
NCBI Full Name: | Transcription factor AP-1 |
NCBI Synonym Full Names: | jun proto-oncogene |
NCBI Official Symbol: | JUN |
NCBI Official Synonym Symbols: | AP1; AP-1; c-Jun |
NCBI Protein Information: | transcription factor AP-1 |
UniProt Protein Name: | Transcription factor AP-1 |
UniProt Synonym Protein Names: | Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 |
Protein Family: | C-Jun-amino-terminal kinase-interacting protein |
UniProt Gene Name: | JUN |
UniProt Entry Name: | JUN_HUMAN |