Anti-Phospho-JNK1-T183/Y185 + JNK2-T183/Y185 + JNK3-T221/Y223 Antibody (CABP1163)
- SKU:
- CABP1163
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-Phospho-JNK1-T183/Y185 + JNK2-T183/Y185 + JNK3-T221/Y223 Antibody |
抗体コード: | CABP1163 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic phosphorylated peptide around T183 & Y185 of human JNK1/2/3 (NP_620637.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | A synthetic phosphorylated peptide around T183 & Y185 of human JNK1/2/3 (NP_620637.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 5599/5601/5602 |
Uniprot: | P45983/P45984/P53779 |
セルラーロケーション: | |
計算された分子量: | 35kDa/44kDa/48kDa/27kDa/52kDa |
観察された分子量: | 46KDa |
同義語: | |
バックグラウンド: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |