Anti-Phospho-INSR-Y1146/IGF1R-Y1131 pAb Antibody (CABP0863)

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SKU:
CABP0863
Product type:
Antibody
Application:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-Phospho-INSR-Y1146/IGF1R-Y1131 Antibody
抗体コード:CABP0863
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human
宿主種:Rabbit
免疫原:A synthetic phosphorylated peptide around Y1146 of human INSR and Y1131 of human IGF1R.
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human
ポジティブサンプル:293T, HeLa
免疫原:A synthetic phosphorylated peptide around Y1146 of human INSR and Y1131 of human IGF1R.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:3643/3480
Uniprot:P06213/P08069
セルラーロケーション:Cell membrane, Single-pass type I membrane protein
計算された分子量:155kDa
観察された分子量:95kDa
Anti-Phospho-INSR-Y1146/IGF1R-Y1131 pAb (CABP0863)Western blot analysis of extracts of various cell lines, using Phospho-INSR-Y1146/IGF1R-Y1131 Rabbit pAb (CABP0863) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
同義語:INSR/IGF1R
バックグラウンド:This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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