Anti-Phospho-GATA1-S310 Antibody (CABP0354)
- SKU:
- CABP0354
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-Phospho-GATA1-S310 Antibody |
抗体コード: | CABP0354 |
抗体サイズ: | 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A phospho specific peptide corresponding to residues surrounding S310 of human GATA1 |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:100 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | K-562 |
免疫原: | A phospho specific peptide corresponding to residues surrounding S310 of human GATA1 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 2623 |
Uniprot: | P15976 |
セルラーロケーション: | Nucleus |
計算された分子量: | 34kDa/35kDa/42kDa |
観察された分子量: | 43kDa |
同義語: | GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT |
バックグラウンド: | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. |
UniProt Protein Function: | Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781). |
NCBI Summary: | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008] |
UniProt Code: | P15976 |
NCBI GenInfo Identifier: | 120956 |
NCBI Gene ID: | 2623 |
NCBI Accession: | P15976.1 |
UniProt Secondary Accession: | P15976,Q96GB8, |
UniProt Related Accession: | P15976 |
Molecular Weight: | 34,232 Da |
NCBI Full Name: | Erythroid transcription factor |
NCBI Synonym Full Names: | GATA binding protein 1 |
NCBI Official Symbol: | GATA1 |
NCBI Official Synonym Symbols: | GF1; GF-1; NFE1; XLTT; ERYF1; NF-E1; XLANP; XLTDA; GATA-1 |
NCBI Protein Information: | erythroid transcription factor |
UniProt Protein Name: | Erythroid transcription factor |
UniProt Synonym Protein Names: | Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein |
Protein Family: | GATA transcription factor |
UniProt Gene Name: | GATA1 |