Anti-Phospho-EIF4B-S422 pAb Antibody (CABP0775)
- SKU:
- CABP0775
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-Phospho-EIF4B-S422 Antibody |
抗体コード: | CABP0775 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic phosphorylated peptide around S422 of human EIF4B (NP_001408.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa |
免疫原: | A synthetic phosphorylated peptide around S422 of human EIF4B (NP_001408.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | TGSE S |
遺伝子ID: | 1975 |
Uniprot: | P23588 |
セルラーロケーション: | |
計算された分子量: | 64kDa/69kDa |
観察された分子量: | 80kDa |
同義語: | EIF4B, EIF-4B, PRO1843 |
バックグラウンド: | Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
UniProt Protein Function: | EIF4B: eukaryotic translation initiation factor 4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. |
UniProt Protein Details: | Protein type:RNA-binding; Translation initiation; Translation Chromosomal Location of Human Ortholog: 12q13.13 Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; polysome Molecular Function:helicase activity; protein binding; ribosomal small subunit binding; RNA binding; RNA strand annealing activity; RNA strand-exchange activity Biological Process: formation of translation preinitiation complex; poly(A) tail shortening; regulation of translational initiation; translational initiation |
UniProt Code: | P23588 |
NCBI GenInfo Identifier: | 205371761 |
NCBI Gene ID: | 1975 |
NCBI Accession: | P23588.2 |
UniProt Secondary Accession: | P23588,Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5, B4DS13 |
UniProt Related Accession: | P23588 |
Molecular Weight: | 64,805 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4B |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4B |
NCBI Official Symbol: | EIF4B |
NCBI Official Synonym Symbols: | EIF-4B; PRO1843 |
NCBI Protein Information: | eukaryotic translation initiation factor 4B |
UniProt Protein Name: | Eukaryotic translation initiation factor 4B |
Protein Family: | Eukaryotic translation initiation factor |
UniProt Gene Name: | EIF4B |
UniProt Entry Name: | IF4B_HUMAN |