Anti-Phospho-CGAS-S420 Antibody (CABP1228)
- SKU:
- CABP1228
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- E330016A19Rik
- Synonyms:
- cGAS
Frequently bought together:
Description
| 抗体名: | Phospho-CGAS-S420 Rabbit pAb |
| 抗体コード: | CABP1228 |
| サイズ: | 50uL, 100uL |
| 同義語: | E330016A19Rik, cGAS |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS. |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | 293T, C6 |
| 免疫原: | A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS. |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 214763 |
| Uniprot: | Q8C6L5 |
| 観察された分子量: | 62KDa |
| バックグラウンド: | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
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