バックグラウンド: | Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. |
UniProt Protein Function: | May play a role in spermatogenesis. |
NCBI Summary: | Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] |
UniProt Code: | Q9BWX1 |
NCBI GenInfo Identifier: | 506325002 |
NCBI Gene ID: | 51533 |
NCBI Accession: | NP_001265150.1 |
UniProt Secondary Accession: | Q9BWX1,K4DI82, |
UniProt Related Accession: | Q9BWX1 |
Molecular Weight: | 39,259 Da |
NCBI Full Name: | PHD finger protein 7 isoform 2 |
NCBI Synonym Full Names: | PHD finger protein 7 |
NCBI Official Symbol: | PHF7 |
NCBI Official Synonym Symbols: | HSPC045; HSPC226; NYD-SP6 |
NCBI Protein Information: | PHD finger protein 7 |
UniProt Protein Name: | PHD finger protein 7 |
UniProt Synonym Protein Names: | Testis development protein NYD-SP6 |
Protein Family: | PHD finger protein |
UniProt Gene Name: | PHF7 |