| UniProt Protein Function: | PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Hydrolase; Secreted; EC 3.5.1.28; Receptor, misc. Chromosomal Location of Human Ortholog: 19p13.12 Molecular Function:N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity Biological Process: defense response to Gram-positive bacterium; detection of bacterium |
| NCBI Summary: | This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011] |
| UniProt Code: | Q96PD5 |
| NCBI GenInfo Identifier: | 38258222 |
| NCBI Gene ID: | 114770 |
| NCBI Accession: | Q96PD5.1 |
| UniProt Secondary Accession: | Q96PD5,Q68CK1, Q96N74, Q9UC60, A8K050, A8K8C7, B2RMZ2 B7ZM33, |
| UniProt Related Accession: | Q96PD5 |
| Molecular Weight: | 68,000 Da |
| NCBI Full Name: | N-acetylmuramoyl-L-alanine amidase |
| NCBI Synonym Full Names: | peptidoglycan recognition protein 2 |
| NCBI Official Symbol: | PGLYRP2 |
| NCBI Official Synonym Symbols: | tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha |
| NCBI Protein Information: | N-acetylmuramoyl-L-alanine amidase |
| UniProt Protein Name: | N-acetylmuramoyl-L-alanine amidase |
| UniProt Synonym Protein Names: | Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L |
| UniProt Gene Name: | PGLYRP2 |
| UniProt Entry Name: | PGRP2_HUMAN |
