Anti-PGLYRP1 Antibody (CAB10460)
- SKU:
- CAB10460
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-PGLYRP1 Antibody |
| 抗体コード: | CAB10460 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human PGLYRP1 (NP_005082.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, LO2, HL-60 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human PGLYRP1 (NP_005082.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QETE DPAC CSPI VPRN EWKA LASE CAQH LSLP LRYV VVSH TAGS SCNT PASC QQQA RNVQ HYHM KTLG WCDV GYNF LIGE DGLV YEGR GWNF TGAH SGHL WNPM SIGI SFMG NYMD RVPT PQAI RAAQ GLLA CGVA QGAL RSNY VLKG HRDV QRTL SPGN QLYH LIQN WPHY RSP |
| 遺伝子ID: | 8993 |
| Uniprot: | O75594 |
| セルラーロケーション: | Cytoplasmic granule, Secreted |
| 計算された分子量: | 21kDa |
| 観察された分子量: | 35kDa |
| 同義語: | PGLYRP1, PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L |
| バックグラウンド: |
| UniProt Protein Function: | PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Apoptosis; Receptor, misc.; Secreted Chromosomal Location of Human Ortholog: 19q13.2-q13.3 Cellular Component: extracellular region Molecular Function:peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; negative regulation of inflammatory response; innate immune response; immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process |
| UniProt Code: | O75594 |
| NCBI GenInfo Identifier: | 18202143 |
| NCBI Gene ID: | 8993 |
| NCBI Accession: | O75594.1 |
| UniProt Secondary Accession: | O75594,Q4VB36, |
| UniProt Related Accession: | O75594 |
| Molecular Weight: | |
| NCBI Full Name: | Peptidoglycan recognition protein 1 |
| NCBI Synonym Full Names: | peptidoglycan recognition protein 1 |
| NCBI Official Symbol: | PGLYRP1 |
| NCBI Official Synonym Symbols: | PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L |
| NCBI Protein Information: | peptidoglycan recognition protein 1; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) |
| UniProt Protein Name: | Peptidoglycan recognition protein 1 |
| UniProt Synonym Protein Names: | Peptidoglycan recognition protein short; PGRP-S |
| Protein Family: | Peptidoglycan recognition protein |
| UniProt Gene Name: | PGLYRP1 |
| UniProt Entry Name: | PGRP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PGLYRP1 antibody (CAB10460) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |