Anti-PGC1 alpha Antibody (CAB17089)
- SKU:
- CAB17089
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PGC1 alpha Antibody |
| 抗体コード: | CAB17089 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of mouse PGC1 alpha (NP_032930.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, HepG2, Mouse spleen, Mouse liver, Mouse kidney, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of mouse PGC1 alpha (NP_032930.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAWD MCSQ DSVW SDIE CAAL VGED QPLC PDLP ELDL SELD VNDL DTDS FLGG LKWC SDQS EIIS NQYN NEPA NIFE KIDE ENEA NLLA VLTE TLDS LPVD EDGL PSFD ALTD GAVT TDNE ASPS SMPD GTPP PQEA EEPS LLKK LLLA PANT QLSY NECS GLST QNHA ANHT HRIR TNPA IVKT ENSW SNKA KSIC QQQK PQRR PCSE LLKY LTTN DDPP HTKP TENR NSSR DKCA SKKK SHTQ PQSQ HAQA KPTT LSLP LTPE SPND PKGS PFEN KTIE RTLS VELS GTAG LTPP TTPP |
| 遺伝子ID: | 19017 |
| Uniprot: | O70343 |
| セルラーロケーション: | |
| 計算された分子量: | 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa |
| 観察された分子量: | 110kDa |
| 同義語: | PPARGC1A, LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, PPARG coactivator 1 alpha, PGC1 alpha, Ppargc1a |
| バックグラウンド: | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. |
| UniProt Code: | O70343 |
| NCBI GenInfo Identifier: | |
| NCBI Gene ID: | |
| NCBI Accession: | |
| UniProt Secondary Accession: | O70343,Q9UBK2, O70343, Q8VHJ7, Q811R2 Q9QYK2, |
| Molecular Weight: | 113kDa |
| NCBI Full Name: | |
| UniProt Protein Name: | |
| UniProt Gene Name: |
 | Western blot analysis of extracts of various cell lines, using PGC1 alpha antibody (CAB17089) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) (CABS003) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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