Anti-PFDN1 Antibody (CAB8681)
- SKU:
- CAB8681
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-PFDN1 Antibody |
| 抗体コード: | CAB8681 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human PFDN1 (NP_002613.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HT-29, PC-12, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human PFDN1 (NP_002613.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAAP VDLE LKKA FTEL QAKV IDTQ QKVK LADI QIEQ LNRT KKHA HLTD TEIM TLVD ETNM YEGV GRMF ILQS KEAI HSQL LEKQ KIAE EKIK ELEQ KKSY LERS VKEA EDNI REML MARR AQ |
| 遺伝子ID: | 5201 |
| Uniprot: | O60925 |
| セルラーロケーション: | |
| 計算された分子量: | 14kDa |
| 観察された分子量: | 14kDa |
| 同義語: | PFDN1, PDF, PFD1 |
| バックグラウンド: | This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. |
| UniProt Protein Function: | PFDN1: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 5q31 Molecular Function:transcription factor activity Biological Process: cell cycle |
| NCBI Summary: | This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60925 |
| NCBI GenInfo Identifier: | 22261811 |
| NCBI Gene ID: | 5201 |
| NCBI Accession: | O60925.2 |
| UniProt Secondary Accession: | O60925,Q53F95, Q96EX6, B2RD02, |
| UniProt Related Accession: | O60925 |
| Molecular Weight: | 14,210 Da |
| NCBI Full Name: | Prefoldin subunit 1 |
| NCBI Synonym Full Names: | prefoldin subunit 1 |
| NCBI Official Symbol: | PFDN1 |
| NCBI Official Synonym Symbols: | PDF; PFD1 |
| NCBI Protein Information: | prefoldin subunit 1 |
| UniProt Protein Name: | Prefoldin subunit 1 |
| Protein Family: | Prefoldin |
| UniProt Gene Name: | PFDN1 |
| UniProt Entry Name: | PFD1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PFDN1 antibody (CAB8681) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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