Anti-PDLIM3 Antibody (CAB6346)
- SKU:
- CAB6346
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-PDLIM3 Antibody |
抗体コード: | CAB6346 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_001107579.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_001107579.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | KAAA HQLC LKID RGET HLWS PQVS EDGK AHPF KINL ESEP QEFK PIGT AHNR RAQP FVAA ANID DKRQ VVSA SYNS PIGL YSTS NIQD ALHG QLRG LIPS SPQN EPTA SVPP ESDV YRML HDNR NEPT QPRQ SGSF RVLQ GMVD DGSD DRPA GTRS VRAP V |
遺伝子ID: | 27295 |
Uniprot: | Q53GG5 |
セルラーロケーション: | Cytoplasm, Z line, myofibril, sarcomere |
計算された分子量: | 20kDa/34kDa/39kDa |
観察された分子量: | 35kDa |
同義語: | PDLIM3, ALP |
バックグラウンド: | The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. |
UniProt Protein Function: | PDLIM3: May play a role in the organization of actin filament arrays within muscle cells. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 4q35 Cellular Component: cytoplasm; Z disc; actin cytoskeleton Molecular Function:protein binding; zinc ion binding; structural constituent of muscle; cytoskeletal protein binding Biological Process: heart development; actin filament organization |
NCBI Summary: | The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012] |
UniProt Code: | Q53GG5 |
NCBI GenInfo Identifier: | 74740479 |
NCBI Gene ID: | 27295 |
NCBI Accession: | Q53GG5.1 |
UniProt Secondary Accession: | Q53GG5,O43590, O60439, O60440, Q8N6Y6, Q9BVP4, B2R866 |
UniProt Related Accession: | Q53GG5 |
Molecular Weight: | 364 |
NCBI Full Name: | PDZ and LIM domain protein 3 |
NCBI Synonym Full Names: | PDZ and LIM domain 3 |
NCBI Official Symbol: | PDLIM3 |
NCBI Official Synonym Symbols: | ALP |
NCBI Protein Information: | PDZ and LIM domain protein 3; enigma homolog; alpha-actinin-2-associated LIM protein |
UniProt Protein Name: | PDZ and LIM domain protein 3 |
UniProt Synonym Protein Names: | Actinin-associated LIM protein; Alpha-actinin-2-associated LIM protein |
Protein Family: | PDZ and LIM domain protein |
UniProt Gene Name: | PDLIM3 |
UniProt Entry Name: | PDLI3_HUMAN |
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