Anti-PDLIM1/CLP36 Antibody (CAB19224)
- SKU:
- CAB19224
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PDLIM1
- Synonyms:
- CLIM1
- Synonyms:
- CLP-36
- Synonyms:
- CLP36
- Synonyms:
- HEL-S-112
- Synonyms:
- hCLIM1
- Synonyms:
- PDZ and LIM domain 1
Frequently bought together:
Description
| 抗体名: | PDLIM1/CLP36 Rabbit mAb |
| 抗体コード: | CAB19224 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | PDLIM1, CLIM1, CLP-36, CLP36, HEL-S-112, hCLIM1, PDZ and LIM domain 1 |
| 申し込み: | WB, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human PDLIM1/CLP36. |
| 申し込み: | WB, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | BxPC-3, THP-1, Mouse thymus |
| 免疫原: | Recombinant protein of human PDLIM1/CLP36. |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9124 |
| Uniprot: | O00151 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 36kDa |
| 観察された分子量: | 36KDa |
| UniProt Protein Function: | CLIM1: a cytoskeletal adaptor protein that bring other proteins to the cytoskeleton. Interacts with alpha-actinins 1, 2 and 4. Recruits the Clik1 kinase to actin stress fibers in nonmuscle cells. Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: transcription factor complex; cytoskeleton; focal adhesion; cytoplasm Molecular Function:zinc ion binding; transcription coactivator activity Biological Process: regulation of transcription, DNA-dependent; response to hypoxia; response to oxidative stress |
| NCBI Summary: | This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012] |
| UniProt Code: | O00151 |
| NCBI GenInfo Identifier: | 20178312 |
| NCBI Gene ID: | 9124 |
| NCBI Accession: | O00151.4 |
| UniProt Secondary Accession: | O00151,Q5VZH5, Q9BPZ9, B2RBS6, |
| UniProt Related Accession: | O00151 |
| Molecular Weight: | 329 |
| NCBI Full Name: | PDZ and LIM domain protein 1 |
| NCBI Synonym Full Names: | PDZ and LIM domain 1 |
| NCBI Official Symbol: | PDLIM1 |
| NCBI Official Synonym Symbols: | CLIM1; CLP36; CLP-36; hCLIM1; HEL-S-112 |
| NCBI Protein Information: | PDZ and LIM domain protein 1; elfin; LIM domain protein CLP-36; epididymis secretory protein Li 112; carboxyl terminal LIM domain protein 1 |
| UniProt Protein Name: | PDZ and LIM domain protein 1 |
| UniProt Synonym Protein Names: | C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36 |
| Protein Family: | PDZ and LIM domain protein |
| UniProt Gene Name: | PDLIM1 |
| UniProt Entry Name: | PDLI1_HUMAN |