| バックグラウンド: | Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. |
| UniProt Protein Function: | Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. |
| NCBI Summary: | Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15113 |
| NCBI GenInfo Identifier: | 6919941 |
| NCBI Gene ID: | 5118 |
| NCBI Accession: | Q15113.2 |
| UniProt Secondary Accession: | Q15113,O14550, B2R9E1, |
| UniProt Related Accession: | Q15113 |
| Molecular Weight: | 47,972 Da |
| NCBI Full Name: | Procollagen C-endopeptidase enhancer 1 |
| NCBI Synonym Full Names: | procollagen C-endopeptidase enhancer |
| NCBI Official Symbol: | PCOLCE |
| NCBI Official Synonym Symbols: | PCPE; PCPE1; PCPE-1 |
| NCBI Protein Information: | procollagen C-endopeptidase enhancer 1 |
| UniProt Protein Name: | Procollagen C-endopeptidase enhancer 1 |
| UniProt Synonym Protein Names: | Procollagen COOH-terminal proteinase enhancer 1; PCPE-1; Procollagen C-proteinase enhancer 1; Type 1 procollagen C-proteinase enhancer protein; Type I procollagen COOH-terminal proteinase enhancer |
| Protein Family: | Procollagen C-endopeptidase enhancer |
| UniProt Gene Name: | PCOLCE |
