Anti-PCM1 Antibody (CAB5696)
- SKU:
- CAB5696
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-PCM1 Antibody |
抗体コード: | CAB5696 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | SW480, 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at 4?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
アイソタイプ: | IgG |
順序: | MATG GGPF EDGM NDQD LPNW SNEN VDDR LNNM DWGA QQKK ANRS SEKN KKKF GVES DKRV TNDI SPES SPGV GRRR TKTP HTFP HSRY MSQM SVPE QAEL EKLK QRIN FSDL DQRS IGSD SQGR ATAA NNKR QLSE NRKP FNFL PMQI NTNK SKDA STSP PNRE TIGS AQCK ELFA SALS NDLL QNCQ VSEE DGRG EPAM ESSQ IVSR LVQI RDYI TKAS SMRE DLVE KNER SANV ERLT HLID HLKE QEKS YMKF LKKI |
遺伝子ID: | 5108 |
Uniprot: | Q15154 |
セルラーロケーション: | Cytoplasm, Cytoplasmic granule, centriolar satellite, centrosome, cilium basal body, cytoskeleton, microtubule organizing center |
計算された分子量: | 59kDa/222kDa/228kDa |
観察された分子量: | 300kDa |
同義語: | PCM1, PTC4, RET/PCM-1 |
バックグラウンド: | The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Code: | Q15154 |
NCBI GenInfo Identifier: | 134142826 |
NCBI Gene ID: | 5108 |
NCBI Accession: | NP_006188.3 |
UniProt Secondary Accession: | Q15154,Q58F13, Q6P1K7, Q8NB85, Q9BWC1, Q9H4A2, |
UniProt Related Accession: | Q15154 |
Molecular Weight: | 59,199 Da |
NCBI Full Name: | pericentriolar material 1 protein |
NCBI Synonym Full Names: | pericentriolar material 1 |
NCBI Official Symbol: | PCM1 |
NCBI Official Synonym Symbols: | PTC4 |
NCBI Protein Information: | pericentriolar material 1 protein; PCM-1; hPCM-1; pericentriolar material 1, PCM1 |
UniProt Protein Name: | Pericentriolar material 1 protein |
Protein Family: | Pericentriolar material 1 protein |
UniProt Gene Name: | PCM1 |
UniProt Entry Name: | PCM1_HUMAN |
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