Anti-PCK2 Antibody (CAB4466)
- SKU:
- CAB4466
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-PCK2 Antibody |
抗体コード: | CAB4466 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human PCK2 |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, 293T, HepG2, Mouse lung, Mouse brain, Mouse spleen, Rat kidney |
免疫原: | A synthesized peptide derived from human PCK2 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 5106 |
Uniprot: | Q16822 |
セルラーロケーション: | |
計算された分子量: | 71kDa |
観察された分子量: | 71KDa |
同義語: | PEPCK, PEPCK-M, PEPCK2 |
バックグラウンド: | This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2014] |
UniProt Protein Function: | PCK2: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Monomer. Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 4.1.1.32; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Kinase, other; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial; Lyase Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:phosphoenolpyruvate carboxykinase (GTP) activity; phosphoenolpyruvate carboxykinase activity; protein binding Biological Process: gluconeogenesis Disease: Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial |
NCBI Summary: | This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of guanosine triphosphate (GTP). A cytosolic form of this protein is encoded by a different gene and is the key enzyme of gluconeogenesis in the liver. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2014] |
UniProt Code: | Q16822 |
NCBI GenInfo Identifier: | 290457671 |
NCBI Gene ID: | 5106 |
NCBI Accession: | Q16822.3 |
UniProt Secondary Accession: | Q16822,O43253, Q86U01, Q9BV62, |
UniProt Related Accession: | Q16822 |
Molecular Weight: | 47,564 Da |
NCBI Full Name: | Phosphoenolpyruvate carboxykinase |
NCBI Synonym Full Names: | phosphoenolpyruvate carboxykinase 2, mitochondrial |
NCBI Official Symbol: | PCK2 |
NCBI Official Synonym Symbols: | PEPCK; PEPCK2; PEPCK-M |
NCBI Protein Information: | phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
UniProt Protein Name: | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
Protein Family: | Protein kinase |
UniProt Gene Name: | PCK2 |
UniProt Entry Name: | PCKGM_HUMAN |
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