Anti-PCDHB4 Antibody (CAB17733)
- SKU:
- CAB17733
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-PCDHB4 Antibody |
| 抗体コード: | CAB17733 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human PCDHB4 (NP_061761.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, Raji, Mouse testis, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human PCDHB4 (NP_061761.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EPIR YSVL EETE SGSF VAHL AKDL GLGI GELA SRSA RVLS DDDK QRLQ LDRQ TGDL LLRE KLDR EELC GPIE PCVL HFQV FLEM PVQF FQGE LLIQ DIND HSPI FPER EVLL KILE NSQP GTLF PLLI AEDL DVGS NGLQ KYTI SPNS HFHI LTRN HSEG KKYP DLVQ DKPL DREE QPEF SLTL VALD GGSP PRSG TVMV RILI MDIN DNAP EFVH TPYG VQVL ENSP LDSP IVRV LARD IDAG NFGS VSYG LFQA SDEI KQTF SINE VTGE I |
| 遺伝子ID: | 56131 |
| Uniprot: | Q9Y5E5 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 87kDa |
 | Western blot - PCDHB4 Rabbit pAb (CAB17733) |
| 同義語: | PCDH-BETA4, PCDHB4 |
| バックグラウンド: | This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | PCDHB4: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 5q31 Cellular Component: intermediate filament cytoskeleton; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane Molecular Function:calcium ion binding Biological Process: synaptic transmission; nervous system development; synaptogenesis; calcium-dependent cell-cell adhesion; cell adhesion; homophilic cell adhesion |
| NCBI Summary: | This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5E5 |
| NCBI GenInfo Identifier: | 9256616 |
| NCBI Gene ID: | 56131 |
| NCBI Accession: | NP_061761.1 |
| UniProt Secondary Accession: | Q9Y5E5,Q4V761, |
| UniProt Related Accession: | Q9Y5E5 |
| Molecular Weight: | 87,270 Da |
| NCBI Full Name: | protocadherin beta-4 |
| NCBI Synonym Full Names: | protocadherin beta 4 |
| NCBI Official Symbol: | PCDHB4 |
| NCBI Official Synonym Symbols: | PCDH-BETA4 |
| NCBI Protein Information: | protocadherin beta-4 |
| UniProt Protein Name: | Protocadherin beta-4 |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDHB4 |
| UniProt Entry Name: | PCDB4_HUMAN |