Anti-PCDH15 Antibody (CAB10086)
- SKU:
- CAB10086
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PCDH15 Antibody |
| 抗体コード: | CAB10086 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SH-SY5Y, 293T, A-549, Raji, Mouse brain, Mouse liver, Mouse spleen, Rat brain, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TVNE LTPV GTTI FTGF SGDN GATD IDDG PNGQ IEYV IQYN PDDP TSND TFEI PLML TGNI VLRK RLNY EDKT RYFV IIQA NDRA QNLN ERRT TTTT LTVD VLDG DDLG PMFL PCVL VPNT RDCR PLTY QAAI PELR TPEE LNPI IVTP PIQA IDQD RNIQ PPSD RPGI LYSI LVGT PEDY PRFF HMHP RTAE LSLL EPVN RDFH QKFD LVIK AEQD NGHP LPAF AGLH IEIL DENN QSPY F |
| 遺伝子ID: | 65217 |
| Uniprot: | Q96QU1 |
| セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
| 計算された分子量: | 92kDa/106kDa/185kDa/197kDa/216kDa |
| 観察された分子量: | 100kDa |
| 同義語: | PCDH15, CDHR15, DFNB23, USH1F |
| バックグラウンド: | This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. |
| UniProt Protein Function: | Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function. |
| NCBI Summary: | This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q96QU1 |
| NCBI GenInfo Identifier: | 115387123 |
| NCBI Gene ID: | 65217 |
| NCBI Accession: | NP_149045.3 |
| UniProt Related Accession: | Q96QU1 |
| Molecular Weight: | |
| NCBI Full Name: | protocadherin-15 isoform CD1-4 |
| NCBI Synonym Full Names: | protocadherin related 15 |
| NCBI Official Symbol: | PCDH15 |
| NCBI Official Synonym Symbols: | USH1F; CDHR15; DFNB23 |
| NCBI Protein Information: | protocadherin-15 |
| UniProt Protein Name: | Protocadherin-15 |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | PCDH15 |
 | Western blot analysis of extracts of various cell lines, using PCDH15 antibody (CAB10086) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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