| UniProt Protein Function: | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation. |
| NCBI Summary: | This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012] |
| UniProt Code: | Q86U86 |
| NCBI GenInfo Identifier: | 73921624 |
| NCBI Gene ID: | 55193 |
| NCBI Accession: | Q86U86.1 |
| UniProt Secondary Accession: | Q86U86,Q1RMD1, Q1RMD2, Q96MS2, Q9H2T3, Q9H2T4, Q9H2T5 Q9H301, Q9H314, A1L381, A1L382, A4FUJ7, |
| UniProt Related Accession: | Q86U86 |
| Molecular Weight: | 184,043 Da |
| NCBI Full Name: | Protein polybromo-1 |
| NCBI Synonym Full Names: | polybromo 1 |
| NCBI Official Symbol: | PBRM1 |
| NCBI Official Synonym Symbols: | PB1; BAF180 |
| NCBI Protein Information: | protein polybromo-1 |
| UniProt Protein Name: | Protein polybromo-1 |
| UniProt Synonym Protein Names: | BRG1-associated factor 180; BAF180; Polybromo-1D |
| Protein Family: | Protein polybromo |
| UniProt Gene Name: | PBRM1 |
| UniProt Entry Name: | PB1_HUMAN |
