Anti-PACSIN2 Antibody (CAB19941)[KO Validated]

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SKU:
CAB19941
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-PACSIN2 Antibody [KO Validated]
抗体コード:CAB19941
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant protein of human PACSIN2.
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse
ポジティブサンプル:HeLa
免疫原:Recombinant protein of human PACSIN2.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:11252
Uniprot:Q9UNF0
セルラーロケーション:Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane
計算された分子量:51kDa/55kDa
観察された分子量:62KDa
Anti-PACSIN2 Antibody [KO Validated] (CAB19941)Western blot analysis of extracts from normal (control) and PACSIN2 knockout (KO) HeLa cells, using PACSIN2 antibody (CAB19941) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
同義語:PACSIN2, SDPII
バックグラウンド:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:PACSIN2: May play a role in vesicle formation and transport. Belongs to the PACSIN family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.2-q13.33

Cellular Component: caveola; cytoplasm; extrinsic to membrane; focal adhesion; intracellular membrane-bound organelle; nucleoplasm; recycling endosome membrane

Molecular Function:identical protein binding; protein binding; transporter activity

Biological Process: cell projection morphogenesis; regulation of endocytosis

NCBI Summary:This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q9UNF0
NCBI GenInfo Identifier:22256968
NCBI Gene ID:11252
NCBI Accession:Q9UNF0.2
UniProt Secondary Accession:Q9UNF0,O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2,
UniProt Related Accession:Q9UNF0
Molecular Weight:51,353 Da
NCBI Full Name:Protein kinase C and casein kinase substrate in neurons protein 2
NCBI Synonym Full Names:protein kinase C and casein kinase substrate in neurons 2
NCBI Official Symbol:PACSIN2  
NCBI Official Synonym Symbols:SDPII  
NCBI Protein Information:protein kinase C and casein kinase substrate in neurons protein 2
UniProt Protein Name:Protein kinase C and casein kinase substrate in neurons protein 2
UniProt Synonym Protein Names:Syndapin-2; Syndapin-II
Protein Family:Protein kinase C and casein kinase substrate in neurons protein
UniProt Gene Name:PACSIN2  
UniProt Entry Name:PACN2_HUMAN
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