Anti-P2RY4 Antibody (CAB3059)
- SKU:
- CAB3059
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-P2RY4 Antibody |
| 抗体コード: | CAB3059 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 286-365 of human P2RY4 (NP_002556.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | BxPC-3, A-549, Mouse stomach, Mouse heart, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 286-365 of human P2RY4 (NP_002556.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VVYK VTRP LASA NSCL DPVL YLLT GDKY RRQL RQLC GGGK PQPR TAAS SLAL VSLP EDSS CRWA ATPQ DSSC STPR ADRL |
| 遺伝子ID: | 5030 |
| Uniprot: | P51582 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 41kDa |
| 同義語: | P2RY4, NRU, P2P, P2Y4, UNR |
| バックグラウンド: | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. |
| UniProt Protein Function: | P2RY4: Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: Xq13 Cellular Component: integral to plasma membrane; basolateral plasma membrane; apical plasma membrane; plasma membrane Molecular Function:purinergic nucleotide receptor activity, G-protein coupled; UTP-activated nucleotide receptor activity; ATP binding; uridine nucleotide receptor activity Biological Process: elevation of cytosolic calcium ion concentration; transepithelial chloride transport; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) |
| NCBI Summary: | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51582 |
| NCBI GenInfo Identifier: | 1709524 |
| NCBI Gene ID: | 5030 |
| NCBI Accession: | P51582.1 |
| UniProt Secondary Accession: | P51582,Q4VBB7, Q4VBB8, Q502W2, Q5JT22, |
| UniProt Related Accession: | P51582 |
| Molecular Weight: | 40,963 Da |
| NCBI Full Name: | P2Y purinoceptor 4 |
| NCBI Synonym Full Names: | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| NCBI Official Symbol: | P2RY4 |
| NCBI Official Synonym Symbols: | NRU; P2P; UNR; P2Y4 |
| NCBI Protein Information: | P2Y purinoceptor 4; uridine nucleotide receptor |
| UniProt Protein Name: | P2Y purinoceptor 4 |
| UniProt Synonym Protein Names: | P2P; Uridine nucleotide receptor; UNR |
| Protein Family: | P2Y purinoceptor |
| UniProt Gene Name: | P2RY4 |
| UniProt Entry Name: | P2RY4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using P2RY4 antibody (CAB3059) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
View AllClose