Anti-P2RY11 Antibody (CAB16940)
- SKU:
- CAB16940
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-P2RY11 Antibody |
| 抗体コード: | CAB16940 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human P2RY11. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Mouse liver, Rat liver |
| 免疫原: | A synthetic peptide of human P2RY11. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 5032 |
| Uniprot: | Q96G91 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 45kDa |
 | Western blot - P2RY11 Rabbit pAb (CAB16940) |
| 同義語: | P2RY11, P2Y11 |
| バックグラウンド: | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. |
| UniProt Protein Function: | P2RY11: Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:ATP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled; receptor activity; neurotransmitter receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; synaptic transmission; adenylate cyclase activation; calcium-mediated signaling; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); defense response; adenosine receptor signaling pathway |
| NCBI Summary: | The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96G91 |
| NCBI GenInfo Identifier: | 21263830 |
| NCBI Gene ID: | 5032 |
| NCBI Accession: | Q96G91.2 |
| UniProt Secondary Accession: | Q96G91,O43190, Q9BYU4, Q9H170, B2R8X9, |
| UniProt Related Accession: | Q96G91 |
| Molecular Weight: | 374 |
| NCBI Full Name: | P2Y purinoceptor 11 |
| NCBI Synonym Full Names: | purinergic receptor P2Y, G-protein coupled, 11 |
| NCBI Official Symbol: | P2RY11 |
| NCBI Official Synonym Symbols: | P2Y11 |
| NCBI Protein Information: | P2Y purinoceptor 11; purinergic receptor P2Y11 |
| UniProt Protein Name: | P2Y purinoceptor 11 |
| Protein Family: | P2Y purinoceptor |
| UniProt Gene Name: | P2RY11 |
| UniProt Entry Name: | P2Y11_HUMAN |