Anti-OTUD5 Antibody (CAB20516)
- SKU:
- CAB20516
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DUBA
- Synonyms:
- MCAND
Frequently bought together:
Description
| I抗体名: | OTUD5 Rabbit pAb |
| 抗体コード: | CAB20516 |
| サイズ: | 50uL, 100uL |
| 同義語: | DUBA, MCAND |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 55593 |
| Uniprot: | Q96G74 |
| 計算された分子量: | 60kDa |
| 観察された分子量: | Refer to figures |
| UniProt Protein Function: | OTUD5: a protein of unknown function. Contains a OTU-like cysteine protease domain. Protein type: Ubiquitin-specific protease; Protease; EC 3.4.19.12 Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytosol Molecular Function: ubiquitin-specific protease activity Biological Process: innate immune response; response to lipopolysaccharide; proteolysis; negative regulation of interferon type I production |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q96G74 |
| NCBI GenInfo Identifier: | 209977019 |
| NCBI Gene ID: | 55593 |
| NCBI Accession: | NP_001129629.1 |
| UniProt Secondary Accession: | Q96G74,Q4KMN9, Q8N6T5, Q9H650, Q9H9U0, Q9NT65, B4DGG7 G5E9D7 |
| UniProt Related Accession: | Q96G74 |
| Molecular Weight: | |
| NCBI Full Name: | OTU domain-containing protein 5 isoform b |
| NCBI Synonym Full Names: | OTU deubiquitinase 5 |
| NCBI Official Symbol: | OTUD5 |
| NCBI Official Synonym Symbols: | DUBA |
| NCBI Protein Information: | OTU domain-containing protein 5; OTU domain containing 5; deubiquinating enzyme A; deubiquitinating enzyme A |
| UniProt Protein Name: | OTU domain-containing protein 5 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme A; DUBA |
| Protein Family: | |
| UniProt Gene Name: | OTUD5 |
| UniProt Entry Name: | OTUD5_HUMAN |
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