Anti-OSBPL8 Antibody (CAB17816)
- SKU:
- CAB17816
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-OSBPL8 Antibody |
| 抗体コード: | CAB17816 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse spleen, Mouse kidney, Rat thymus, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OSBPL8 (NP_065892.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEGG LADG EPDR TSLL GDSK DVLG PSTV VANS DESQ LLTP GKMS QRQG KEAY PTPT KDLH QPSL SPAS PHSQ GFER GKED ISQN KDES SLSM SKSK SESK LYNG SEKD SS |
| 遺伝子ID: | 114882 |
| Uniprot: | Q9BZF1 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 101kDa |
 | Western blot - OSBPL8 Rabbit pAb (CAB17816) |
| 同義語: | MST120, MSTP120, ORP8, OSBP10, OSBPL8 |
| バックグラウンド: | This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| UniProt Protein Function: | OSBPL8: a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two splice variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 12q14 Cellular Component: membrane Molecular Function:cholesterol binding; phosphatidylserine binding; phospholipid transporter activity Biological Process: activation of protein kinase B; fat cell differentiation; phospholipid transport; positive regulation of protein kinase B signaling cascade |
| NCBI Summary: | This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| UniProt Code: | Q9BZF1 |
| NCBI GenInfo Identifier: | 84627542 |
| NCBI Gene ID: | 114882 |
| NCBI Accession: | BC111728 |
| UniProt Secondary Accession: | Q9BZF1,Q52LQ3, Q68D75, Q8WXP8, Q9P277, A8K1T2, E9PE66 E9PE68, |
| UniProt Related Accession: | Q9BZF1 |
| Molecular Weight: | 96,956 Da |
| NCBI Full Name: | Homo sapiens oxysterol binding protein-like 8, transcript variant 1, mRNA |
| NCBI Synonym Full Names: | oxysterol binding protein like 8 |
| NCBI Official Symbol: | OSBPL8 |
| NCBI Official Synonym Symbols: | ORP8; MST120; OSBP10; MSTP120 |
| NCBI Protein Information: | oxysterol-binding protein-related protein 8 |
| UniProt Protein Name: | Oxysterol-binding protein-related protein 8 |
| Protein Family: | Oxysterol-binding protein-related protein |
| UniProt Gene Name: | OSBPL8 |
| UniProt Entry Name: | OSBL8_HUMAN |