Anti-OPRD1 Antibody (CAB8445)
- SKU:
- CAB8445
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-OPRD1 Antibody |
| 抗体コード: | CAB8445 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRD1 (NP_000902.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human OPRD1 (NP_000902.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LHLC IALG YANS SLNP VLYA FLDE NFKR CFRQ LCRK PCGR PDPS SFSR AREA TARE RVTA CTPS DGPG GGAA A |
| 遺伝子ID: | 4985 |
| Uniprot: | P41143 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 43kDa |
| 同義語: | OPRD1, OPRD |
| バックグラウンド: |
| UniProt Protein Function: | DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.1-p34.3 Cellular Component: cytoplasm; integral to plasma membrane; intrinsic to plasma membrane; lipid raft; nerve terminal; neuron projection; plasma membrane; postsynaptic membrane; vesicle Molecular Function:neuropeptide binding; opioid receptor activity; protein binding Biological Process: activation of CREB transcription factor; adult locomotory behavior; eating behavior; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; negative regulation of protein oligomerization; neuropeptide signaling pathway; positive regulation of peptidyl-serine phosphorylation; protein import into nucleus, translocation; regulation of calcium ion transport; regulation of mitochondrial membrane potential; regulation of sensory perception of pain; synaptic transmission |
| UniProt Code: | P41143 |
| NCBI GenInfo Identifier: | 311033488 |
| NCBI Gene ID: | 4985 |
| NCBI Accession: | P41143.4 |
| UniProt Secondary Accession: | P41143,B5B0B8, |
| UniProt Related Accession: | P41143 |
| Molecular Weight: | 40,369 Da |
| NCBI Full Name: | Delta-type opioid receptor |
| NCBI Synonym Full Names: | opioid receptor delta 1 |
| NCBI Official Symbol: | OPRD1 |
| NCBI Official Synonym Symbols: | OPRD |
| NCBI Protein Information: | delta-type opioid receptor |
| UniProt Protein Name: | Delta-type opioid receptor |
| Protein Family: | Delta-type opioid receptor |
| UniProt Gene Name: | OPRD1 |
| UniProt Entry Name: | OPRD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OPRD1 antibody (CAB8445) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |