Anti-OASL Antibody (CAB10527)
- SKU:
- CAB10527
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-OASL Antibody |
| 抗体コード: | CAB10527 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 315-514 of human OASL (NP_003724.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:1000 |
| 反応性: | Human |
| ポジティブサンプル: | MCF7, SH-SY5Y |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 315-514 of human OASL (NP_003724.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EGYR WDIV AQRA SQCL KQDC CYDN RENP ISSW NVKR ARDI HLTV EQRG YPDF NLIV NPYE PIRK VKEK IRRT RGYS GLQR LSFQ VPGS ERQL LSSR CSLA KYGI FSHT HIYL LETI PSEI QVFV KNPD GGSY AYAI NPNS FILG LKQQ IEDQ QGLP KKQQ QLEF QGQV LQDW LGLG IYGI QDSD TLIL SKKK GEAL FPAS |
| 遺伝子ID: | 8638 |
| Uniprot: | Q15646 |
| セルラーロケーション: | Cytoplasm, Nucleus, nucleolus |
| 計算された分子量: | 29kDa/43kDa/59kDa |
| 観察された分子量: | 75kDa |
| 同義語: | OASL, OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL |
| バックグラウンド: |
| UniProt Protein Function: | OASL: a protein of the 2'-5'-oligoadenylate synthetase family, but does not have 2'-5'-OAS activity. Binds double-stranded RNA and DNA. Interacts with the ligand binding domain of the thyroid receptor (TR). Does not require the presence of thyroid hormone for its interaction. Contains a ubiquitin-like domain that interacts with methyl CpG-binding protein 1. |
| UniProt Protein Details: | Protein type:DNA-binding; Nucleolus Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: cytoplasm; cytosol; membrane; nucleolus; nucleoplasm Molecular Function:2'-5'-oligoadenylate synthetase activity; DNA binding; double-stranded RNA binding; RNA binding; thyroid hormone receptor binding Biological Process: negative regulation of viral genome replication; response to virus |
| UniProt Code: | Q15646 |
| NCBI GenInfo Identifier: | 6226835 |
| NCBI Gene ID: | 8638 |
| NCBI Accession: | Q15646.2 |
| UniProt Secondary Accession: | Q15646,O75686, Q17R95, Q9Y6K6, Q9Y6K7, B2RAZ2, I1YDD2 |
| UniProt Related Accession: | Q15646 |
| Molecular Weight: | 59kDa |
| NCBI Full Name: | 2'-5'-oligoadenylate synthase-like protein |
| NCBI Synonym Full Names: | 2'-5'-oligoadenylate synthetase like |
| NCBI Official Symbol: | OASL |
| NCBI Official Synonym Symbols: | OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL |
| NCBI Protein Information: | 2'-5'-oligoadenylate synthase-like protein |
| UniProt Protein Name: | 2'-5'-oligoadenylate synthase-like protein |
| UniProt Synonym Protein Names: | 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 59 kDa 2'-5'-oligoadenylate synthase-like protein; Thyroid receptor-interacting protein 14; TR-interacting protein 14; TRIP-14; p59 OASL; p59OASL |
| Protein Family: | 2'-5'-oligoadenylate synthase-like protein |
| UniProt Gene Name: | OASL |
 | Western blot analysis of extracts of various cell lines, using OASL antibody (CAB10527) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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