Anti-NUP43 Antibody (CAB15983)
- SKU:
- CAB15983
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-NUP43 Antibody |
| 抗体コード: | CAB15983 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | OVCAR3, HeLa, Rat spleen , Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DGRI NLFR ADHK EAVR TIDN ADSS TLHA VTFL RTPE ILTV NSIG QLKI WDFR QQGN EPSQ ILSL TGDR VPLH CVDR HPNQ QHVV ATGG QDGM LSIW DVRQ GTMP VSLL KAH |
| 遺伝子ID: | 348995 |
| Uniprot: | Q8NFH3 |
| セルラーロケーション: | Chromosome, Nucleus, centromere, kinetochore, nuclear pore complex |
| 計算された分子量: | 31kDa/42kDa |
| 観察された分子量: | 42kDa |
| 同義語: | NUP43, bA350J20.1, p42 |
| バックグラウンド: | Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]). |
| UniProt Protein Function: | NUP43: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Nucleoporin Chromosomal Location of Human Ortholog: 6q25.1 Cellular Component: cytosol; kinetochore; nuclear envelope Molecular Function:protein binding Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein sumoylation; RNA-mediated gene silencing; sister chromatid cohesion; tRNA export from nucleus; viral reproduction; viral transcription |
| NCBI Summary: | Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NFH3 |
| NCBI GenInfo Identifier: | 27923819 |
| NCBI Gene ID: | 348995 |
| NCBI Accession: | Q8NFH3.1 |
| UniProt Secondary Accession: | Q8NFH3,Q9H8S0, B4E2F0, |
| UniProt Related Accession: | Q8NFH3 |
| Molecular Weight: | 31,512 Da |
| NCBI Full Name: | Nucleoporin Nup43 |
| NCBI Synonym Full Names: | nucleoporin 43 |
| NCBI Official Symbol: | NUP43 |
| NCBI Official Synonym Symbols: | p42; bA350J20.1 |
| NCBI Protein Information: | nucleoporin Nup43 |
| UniProt Protein Name: | Nucleoporin Nup43 |
| UniProt Synonym Protein Names: | Nup107-160 subcomplex subunit Nup43; p42 |
| Protein Family: | Nucleoporin |
| UniProt Gene Name: | NUP43 |
| UniProt Entry Name: | NUP43_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NUP43 antibody (CAB15983) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |