Anti-NUDT9 Antibody (CAB12220)
- SKU:
- CAB12220
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NUDT9 Antibody |
| 抗体コード: | CAB12220 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human NUDT9 (NP_076952.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, HeLa, Mouse brain, Mouse testis, Rat heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human NUDT9 (NP_076952.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VMSG SNGS KENS HNKA RTSP YPGS KVER SQVP NEKV GWLV EWQD YKPV EYTA VSVL AGPR WADP QISE SNFS PKFN EKDG HVER KSKN GLYE IENG RPRN PAGR TGLV GRGL LGRW GPNH AADP IITR WKRD SSGN KIMH PVSG KHIL QFVA IKRK DCGE WAIP GGMV DPGE KISA TLKR EFGE EALN SLQK TSAE KREI EEKL HKLF SQD |
| 遺伝子ID: | 53343 |
| Uniprot: | Q9BW91 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 33kDa/39kDa |
| 観察された分子量: | 39kDa |
| 同義語: | NUDT9, NUDT10 |
| バックグラウンド: | The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | NUDT9: Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'- phosphate. Belongs to the Nudix hydrolase family. NudF subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.6.1.13; Hydrolase; Mitochondrial; Nucleotide Metabolism - purine Chromosomal Location of Human Ortholog: 4q22.1 Cellular Component: cell junction; mitochondrial matrix; mitochondrion; nuclear membrane Molecular Function:adenosine-diphosphatase activity; ADP-ribose diphosphatase activity |
| NCBI Summary: | The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9BW91 |
| NCBI GenInfo Identifier: | 20455184 |
| NCBI Gene ID: | 53343 |
| NCBI Accession: | Q9BW91.1 |
| UniProt Secondary Accession: | Q9BW91,Q8NBN1, Q8NCB9, Q8NG25, |
| UniProt Related Accession: | Q9BW91 |
| Molecular Weight: | 39kDa |
| NCBI Full Name: | ADP-ribose pyrophosphatase, mitochondrial |
| NCBI Synonym Full Names: | nudix hydrolase 9 |
| NCBI Official Symbol: | NUDT9 |
| NCBI Official Synonym Symbols: | NUDT10 |
| NCBI Protein Information: | ADP-ribose pyrophosphatase, mitochondrial |
| UniProt Protein Name: | ADP-ribose pyrophosphatase, mitochondrial |
| UniProt Synonym Protein Names: | ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9 |
| Protein Family: | Nudix hydrolase |
| UniProt Gene Name: | NUDT9 |
 | Western blot analysis of extracts of various cell lines, using NUDT9 antibody (CAB12220) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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