Anti-NRL Antibody (CAB16935)
- SKU:
- CAB16935
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-NRL Antibody |
抗体コード: | CAB16935 |
抗体サイズ: | 20uL, 50 uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide of human NRL. |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | A synthetic peptide of human NRL. |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 4901 |
Uniprot: | P54845 |
セルラーロケーション: | |
計算された分子量: | 11kDa/25kDa |
観察された分子量: | Refer to figures |
同義語: | NRL, D14S46E, NRL-MAF, RP27 |
バックグラウンド: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. |
UniProt Protein Function: | Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001). |
NCBI Summary: | This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008] |
UniProt Code: | P54845 |
NCBI GenInfo Identifier: | 5453802 |
NCBI Gene ID: | 4901 |
NCBI Accession: | NP_006168.1 |
UniProt Secondary Accession: | P54845,Q53XD0, A8MX14, |
UniProt Related Accession: | P54845 |
Molecular Weight: | 11,276 Da |
NCBI Full Name: | neural retina-specific leucine zipper protein isoform 1 |
NCBI Synonym Full Names: | neural retina leucine zipper |
NCBI Official Symbol: | NRL |
NCBI Official Synonym Symbols: | RP27; D14S46E; NRL-MAF |
NCBI Protein Information: | neural retina-specific leucine zipper protein |
UniProt Protein Name: | Neural retina-specific leucine zipper protein |
Protein Family: | Neural retina-specific leucine zipper protein |
UniProt Gene Name: | NRL |