Anti-NQO2 Antibody (CAB3846)
- SKU:
- CAB3846
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NQO2 Antibody |
| 抗体コード: | CAB3846 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human NQO2 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Mouse kidney, Mouse thymus, Rat kidney |
| 免疫原: | A synthesized peptide derived from human NQO2 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 4835 |
| Uniprot: | P16083 |
| セルラーロケーション: | |
| 計算された分子量: | 26kDa |
| 観察された分子量: | 26KDa |
| 同義語: | DHQV, DIA6, NMOR2, QR2 |
| バックグラウンド: | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Protein Function: | NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.10.99.2 Chromosomal Location of Human Ortholog: 6p25.2 Cellular Component: nucleoplasm; cytoplasm Molecular Function:electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding Biological Process: memory Disease: Breast Cancer |
| NCBI Summary: | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | P16083 |
| NCBI GenInfo Identifier: | 317373581 |
| NCBI Gene ID: | 4835 |
| NCBI Accession: | P16083.5 |
| UniProt Secondary Accession: | P16083,Q9JI75, |
| UniProt Related Accession: | P16083 |
| Molecular Weight: | 231 |
| NCBI Full Name: | Ribosyldihydronicotinamide dehydrogenase |
| NCBI Synonym Full Names: | NAD(P)H dehydrogenase, quinone 2 |
| NCBI Official Symbol: | NQO2 |
| NCBI Official Synonym Symbols: | QR2; DHQV; DIA6; NMOR2 |
| NCBI Protein Information: | ribosyldihydronicotinamide dehydrogenase [quinone]; ribosyldihydronicotinamide dehydrogenase [quinone]; quinone reductase 2; NRH:quinone oxidoreductase 2; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2 |
| UniProt Protein Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| UniProt Synonym Protein Names: | NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2 |
| Protein Family: | NADH-quinone oxidoreductase |
| UniProt Gene Name: | NQO2 |
| UniProt Entry Name: | NQO2_HUMAN |
 | Western blot - NQO2 Rabbit mAb (CAB3846) |
View AllClose