Anti-NPTX2 Antibody (CAB12031)
- SKU:
- CAB12031
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NPTX2 Antibody |
| 抗体コード: | CAB12031 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-240 of human NPTX2 (NP_002514.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | SH-SY5Y, BxPC-3, LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-240 of human NPTX2 (NP_002514.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KLAR CEGL AGGK ARGA GATG KDTM GDLP RDPG HVVE QLSR SLQT LKDR LESL EHQL RANV SNAG LPGD FREV LQQR LGEL ERQL LRKV AELE DEKS LLHN ETSA HRQK TEST LNAL LQRV TELE RGNS AFKS PDAF KVSL PLRT NYLY GKI |
| 遺伝子ID: | 4885 |
| Uniprot: | P47972 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 47kDa |
| 観察された分子量: | 47kDa |
| 同義語: | NPTX2, NARP, NP-II, NP2 |
| バックグラウンド: | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. |
| UniProt Protein Function: | NPTX2: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 7q21.3-q22.1 |
| NCBI Summary: | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009] |
| UniProt Code: | P47972 |
| NCBI GenInfo Identifier: | 20981708 |
| NCBI Gene ID: | 4885 |
| NCBI Accession: | P47972.2 |
| UniProt Secondary Accession: | P47972,Q86XV7, Q96G70, A4D267, |
| UniProt Related Accession: | P47972 |
| Molecular Weight: | 47,042 Da |
| NCBI Full Name: | Neuronal pentraxin-2 |
| NCBI Synonym Full Names: | neuronal pentraxin 2 |
| NCBI Official Symbol: | NPTX2 |
| NCBI Official Synonym Symbols: | NP2; NARP; NP-II |
| NCBI Protein Information: | neuronal pentraxin-2 |
| UniProt Protein Name: | Neuronal pentraxin-2 |
| UniProt Synonym Protein Names: | Neuronal pentraxin II; NP-II |
| Protein Family: | Neuronal pentraxin |
| UniProt Gene Name: | NPTX2 |
| UniProt Entry Name: | NPTX2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NPTX2 antibody (CAB12031) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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