Anti-NOVA1 Antibody (CAB12030)
- SKU:
- CAB12030
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-NOVA1 Antibody |
抗体コード: | CAB12030 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 408-507 of human NOVA1 (NP_002506.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | U-251MG, SH-SY5Y |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 408-507 of human NOVA1 (NP_002506.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SAIL GTEK STDG SKDV VEIA VPEN LVGA ILGK GGKT LVEY QELT GARI QISK KGEF VPGT RNRK VTIT GTPA ATQA AQYL ITQR ITYE QGVR AANP QKVG |
遺伝子ID: | 4857 |
Uniprot: | P51513 |
セルラーロケーション: | Nucleus |
計算された分子量: | 19kDa/49kDa/51kDa/52kDa |
観察された分子量: | 60kDa |
同義語: | NOVA1, Nova-1 |
バックグラウンド: | This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. |
UniProt Protein Function: | NOVA1: May regulate RNA splicing or metabolism in a specific subset of developing neurons. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; RNA splicing Chromosomal Location of Human Ortholog: 14q Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Molecular Function:RNA binding Biological Process: locomotory behavior; RNA processing; RNA splicing; synaptic transmission |
NCBI Summary: | This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51513 |
NCBI GenInfo Identifier: | 1709303 |
NCBI Gene ID: | 4857 |
NCBI Accession: | P51513.1 |
UniProt Secondary Accession: | P51513,Q6B004, A8K0S4, A8K4Q7, D3DS81, D3DS82, |
UniProt Related Accession: | P51513 |
Molecular Weight: | 49,253 Da |
NCBI Full Name: | RNA-binding protein Nova-1 |
NCBI Synonym Full Names: | NOVA alternative splicing regulator 1 |
NCBI Official Symbol: | NOVA1 |
NCBI Official Synonym Symbols: | Nova-1 |
NCBI Protein Information: | RNA-binding protein Nova-1 |
UniProt Protein Name: | RNA-binding protein Nova-1 |
UniProt Synonym Protein Names: | Neuro-oncological ventral antigen 1; Onconeural ventral antigen 1; Paraneoplastic Ri antigen; Ventral neuron-specific protein 1 |
Protein Family: | RNA-binding protein |
UniProt Gene Name: | NOVA1 |
UniProt Entry Name: | NOVA1_HUMAN |
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