Anti-NOSIP Antibody (CAB10024)
- SKU:
- CAB10024
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-NOSIP Antibody |
| 抗体コード: | CAB10024 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human NOSIP (NP_057037.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-549, B cells, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-301 of human NOSIP (NP_057037.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MTRH GKNC TAGA VYTY HEKK KDTA ASGY GTQN IRLS RDAV KDFD CCCL SLQP CHDP VVTP DGYL YERE AILE YILH QKKE IARQ MKAY EKQR GTRR EEQK ELQR AASQ DHVR GFLE KESA IVSR PLNP FTAK ALSG TSPD DVQP GPSV GPPS KDKD KVLP SFWI PSLT PEAK ATKL EKPS RTVT CPMS GKPL RMSD LTPV HFTP LDSS VDRV GLIT RSER YVCA VTRD SLSN ATPC AVLR PSGA VVTL ECVE KLIR KDMV DPVT GDKL TDRD IIVL QRGG TGFA GSGV KLQA EKSR PVMQ A |
| 遺伝子ID: | 51070 |
| Uniprot: | Q9Y314 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 33kDa |
| 観察された分子量: | 35kDa |
| 同義語: | NOSIP, CGI-25 |
| バックグラウンド: | The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. |
| UniProt Protein Function: | NOSIP: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity. Belongs to the NOSIP family. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: cytoplasm; cytosol; Golgi membrane; nucleus Molecular Function:protein binding Biological Process: negative regulation of catalytic activity; negative regulation of nitric-oxide synthase activity; regulation of nitric-oxide synthase activity |
| NCBI Summary: | The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012] |
| UniProt Code: | Q9Y314 |
| NCBI GenInfo Identifier: | 74735248 |
| NCBI Gene ID: | 51070 |
| NCBI Accession: | Q9Y314.1 |
| UniProt Secondary Accession: | Q9Y314,Q96FD2, |
| UniProt Related Accession: | Q9Y314 |
| Molecular Weight: | 33,172 Da |
| NCBI Full Name: | Nitric oxide synthase-interacting protein |
| NCBI Synonym Full Names: | nitric oxide synthase interacting protein |
| NCBI Official Symbol: | NOSIP |
| NCBI Official Synonym Symbols: | CGI-25 |
| NCBI Protein Information: | nitric oxide synthase-interacting protein |
| UniProt Protein Name: | Nitric oxide synthase-interacting protein |
| UniProt Synonym Protein Names: | E3 ubiquitin-protein ligase NOSIP (EC:6.3.2.-); eNOS-interacting protein |
| Protein Family: | Nitric oxide synthase-interacting protein |
| UniProt Gene Name: | NOSIP |
| UniProt Entry Name: | NOSIP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NOSIP antibody (CAB10024) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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