Anti-NOP56 Antibody (CAB8040)
- SKU:
- CAB8040
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | NOP56 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8040 |
| 抗体サイズ: | 100µL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human NOP56 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant protein of human NOP56 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10528 |
| Uniprot: | O00567 |
| セルラーロケーション: | Cytoplasm, Nucleus, nucleolus, nucleoplasm |
| 計算された分子量: | 66kDa |
| 観察された分子量: | 66kDa |
| 同義語: | NOP56, NOL5A, SCA36 |
| バックグラウンド: | Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. |
| UniProt Protein Function: | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. |
| NCBI Summary: | Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016] |
| UniProt Code: | O00567 |
| NCBI GenInfo Identifier: | 32483374 |
| NCBI Gene ID: | 10528 |
| NCBI Accession: | NP_006383 |
| UniProt Related Accession: | O00567 |
| Molecular Weight: | 66kDa |
| NCBI Full Name: | nucleolar protein 56 |
| NCBI Synonym Full Names: | NOP56 ribonucleoprotein |
| NCBI Official Symbol: | NOP56 |
| NCBI Official Synonym Symbols: | NOL5A; SCA36 |
| NCBI Protein Information: | nucleolar protein 56 |
| UniProt Protein Name: | Nucleolar protein 56 |
| UniProt Synonym Protein Names: | Nucleolar protein 5A |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP56 |
 | Western blot analysis of extracts of HeLa cells, using NOP56 antibody (CAB8040). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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