| UniProt Protein Function: | Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs. |
| NCBI Summary: | Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016] |
| UniProt Code: | O00567 |
| NCBI GenInfo Identifier: | 32483374 |
| NCBI Gene ID: | 10528 |
| NCBI Accession: | NP_006383 |
| UniProt Related Accession: | O00567 |
| Molecular Weight: | 66kDa |
| NCBI Full Name: | nucleolar protein 56 |
| NCBI Synonym Full Names: | NOP56 ribonucleoprotein |
| NCBI Official Symbol: | NOP56 |
| NCBI Official Synonym Symbols: | NOL5A; SCA36 |
| NCBI Protein Information: | nucleolar protein 56 |
| UniProt Protein Name: | Nucleolar protein 56 |
| UniProt Synonym Protein Names: | Nucleolar protein 5A |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP56 |
