Anti-NOCT Antibody (CAB15805)
- SKU:
- CAB15805
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NOCT Antibody |
| 抗体コード: | CAB15805 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human NOCT (NP_036250.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 132-431 of human NOCT (NP_036250.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LRTD CPST HPPI RVMQ WNIL AQAL GEGK DNFV QCPV EALK WEER KCLI LEEI LAYQ PDIL CLQE VDHY FDTF QPLL SRLG YQGT FFPK PWSP CLDV EHNN GPDG CALF FLQN RFKL VNSA NIRL TAMT LKTN QVAI AQTL ECKE SGRQ FCIA VTHL KART GWER FRSA QGCD LLQN LQNI TQGA KIPL IVCG DFNA EPTE EVYK HFAS SSLN LNSA YKLL SADG QSEP PYTT WKIR TSGE CRHT LDYI WYSK HALN VRSA LDLL TEEQ IGPN RLPS FNYP SDHL SLVC DFSF TEES DGLS |
| 遺伝子ID: | 25819 |
| Uniprot: | Q9UK39 |
| セルラーロケーション: | Cytoplasm, Nucleus, perinuclear region |
| 計算された分子量: | 48kDa |
| 観察された分子量: | 48kDa |
| 同義語: | NOCT, CCR4L, CCRN4L, Ccr4c, NOC, nocturnin |
| バックグラウンド: | The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. |
| UniProt Protein Function: | CCRN4L: Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases. Belongs to the CCR4/nocturin family. |
| UniProt Protein Details: | Protein type:EC 3.1.13.4 Chromosomal Location of Human Ortholog: 4q31.1 Cellular Component: cytoplasm; nucleoplasm; nucleus; perinuclear region of cytoplasm Molecular Function:mRNA binding; poly(A)-specific ribonuclease activity; transcription factor activity Biological Process: circadian regulation of gene expression; circadian rhythm; mRNA stabilization; negative regulation of osteoblast differentiation; positive regulation of fat cell differentiation; regulation of circadian rhythm; response to extracellular stimulus; response to lipopolysaccharide; transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UK39 |
| NCBI GenInfo Identifier: | 212276446 |
| NCBI Gene ID: | 25819 |
| NCBI Accession: | Q9UK39.2 |
| UniProt Secondary Accession: | Q9UK39,Q14D51, Q9HD93, Q9HD94, Q9HD95, D3DNY5, |
| UniProt Related Accession: | Q9UK39 |
| Molecular Weight: | 48,196 Da |
| NCBI Full Name: | Nocturnin |
| NCBI Synonym Full Names: | nocturnin |
| NCBI Official Symbol: | NOCT |
| NCBI Official Synonym Symbols: | NOC; CCR4L; Ccr4c; CCRN4L |
| NCBI Protein Information: | nocturnin |
| UniProt Protein Name: | Nocturnin |
| UniProt Synonym Protein Names: | Carbon catabolite repression 4-like protein; Circadian deadenylase NOC |
| UniProt Gene Name: | NOCT |
| UniProt Entry Name: | NOCT_HUMAN |
 | Western blot analysis of extracts of rat brain, using NOCT antibody (CAB15805) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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