Anti-NOB1 Antibody (CAB17690)
- SKU:
- CAB17690
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-NOB1 Antibody |
| 抗体コード: | CAB17690 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NOB1 (NP_054781.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | BxPC-3, LO2, rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NOB1 (NP_054781.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAPV EHVV ADAG AFLR HAAL QDIG KNIY TIRE VVTE IRDK ATRR RLAV LPYE LRFK EPLP EYVR LVTE FSKK TGDY PSLS ATDI QVLA LTYQ LEAE FVGV SHLK QEPQ KVKV SSSI QHPE TPLH ISGF HLPY KPKP PQET EKGH SACE PENL EFSS FMFW RNPL PNID HELQ ELLI DRGE DVPS EEEE EEEN GFED RKDD SDDD GGGW ITPS NIKQ IQQE LEQC DVPE DV |
| 遺伝子ID: | 28987 |
| Uniprot: | Q9ULX3 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 47kDa |
 | Western blot - NOB1 Polyclonal Antibody (CAB17690) |
| 同義語: | ART-4, MST158, MSTP158, NOB1P, PSMD8BP1, NOB1 |
| バックグラウンド: | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010] |
| UniProt Protein Function: | NOB1P: May play a role in mRNA degradation. Belongs to the NOB1 family. |
| UniProt Protein Details: | Protein type:RNA processing Chromosomal Location of Human Ortholog: 16q22.3 Cellular Component: cytosol; nucleolar preribosome, small subunit precursor; nucleoplasm Molecular Function:endoribonuclease activity Biological Process: cleavages during rRNA processing; maturation of SSU-rRNA; rRNA processing |
| NCBI Summary: | In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | Q9ULX3 |
| NCBI GenInfo Identifier: | 74753398 |
| NCBI Gene ID: | 28987 |
| NCBI Accession: | Q9ULX3.1 |
| UniProt Secondary Accession: | Q9ULX3,Q7L6B7, Q7M4M4, Q7Z4B5, Q9NWB0, |
| UniProt Related Accession: | Q9ULX3 |
| Molecular Weight: | 46,675 Da |
| NCBI Full Name: | RNA-binding protein NOB1 |
| NCBI Synonym Full Names: | NIN1/PSMD8 binding protein 1 homolog |
| NCBI Official Symbol: | NOB1 |
| NCBI Official Synonym Symbols: | ART-4; NOB1P; MST158; MSTP158; PSMD8BP1 |
| NCBI Protein Information: | RNA-binding protein NOB1 |
| UniProt Protein Name: | RNA-binding protein NOB1 |
| UniProt Synonym Protein Names: | Phosphorylation regulatory protein HP-10; Protein ART-4 |
| Protein Family: | Endoribonuclease |
| UniProt Gene Name: | NOB1 |
| UniProt Entry Name: | NOB1_HUMAN |