Anti-NMUR2 Antibody (CAB12812)
- SKU:
- CAB12812
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| 抗体名: | Anti-NMUR2 Antibody |
| 抗体コード: | CAB12812 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_064552.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SGC-7901, Mouse uterus, Mouse small intestine, Rat uterus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 326-415 of human NMUR2 (NP_064552.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IYNL LSRR FQAA FQNV ISSF HKQW HSQH DPQL PPAQ RNIF LTEC HFVE LTED IGPQ FPCQ SSMH NSHL PAAL SSEQ MSRT NYQS FHFN KT |
| 遺伝子ID: | 56923 |
| Uniprot: | Q9GZQ4 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 47kDa |
| 観察された分子量: | 48kDa |
| 同義語: | NMUR2, FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1 |
| バックグラウンド: | This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. |
| UniProt Protein Function: | NMUR2: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 5q33.1 Cellular Component: integral to membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; GTP binding; intracellular calcium activated chloride channel activity; neuromedin U binding; neuromedin U receptor activity; protein binding Biological Process: arachidonic acid secretion; calcium ion transport; calcium-dependent phospholipase A2 activation; cell-cell signaling; central nervous system development; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inositol phosphate-mediated signaling |
| NCBI Summary: | This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9GZQ4 |
| NCBI GenInfo Identifier: | 311033403 |
| NCBI Gene ID: | 56923 |
| NCBI Accession: | Q9GZQ4.2 |
| UniProt Secondary Accession: | Q9GZQ4,Q7LC54, Q96AM5, Q9NRA6, |
| UniProt Related Accession: | Q9GZQ4 |
| Molecular Weight: | 48kDa |
| NCBI Full Name: | Neuromedin-U receptor 2 |
| NCBI Synonym Full Names: | neuromedin U receptor 2 |
| NCBI Official Symbol: | NMUR2 |
| NCBI Official Synonym Symbols: | FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2 |
| NCBI Protein Information: | neuromedin-U receptor 2 |
| UniProt Protein Name: | Neuromedin-U receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1 |
| Protein Family: | Neuromedin-U receptor |
| UniProt Gene Name: | NMUR2 |
 | Western blot analysis of extracts of various cell lines, using NMUR2 antibody (CAB12812) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |