Anti-NLRP11 Antibody (CAB12132)

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SKU:
CAB12132
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-NLRP11 Antibody
抗体コード:CAB12132
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IF
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2).
申し込み:WB IF
推奨希釈:WB 1:500 - 1:2000 IF 1:50 - 1:200
反応性:Human
ポジティブサンプル:293T
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:VGFT EADV SVLQ AANI LLPS NTHK DRYK FIHL NVQE FCTA IAFL MAVP NYLI PSGS REYK EKRE QYSD FNQV FTFI FGLL NANR RKIL ETSF GYQL PMVD SFKW YSVG YMKH LDRD PEKL THHM PLFY CLYE NREE EFVK TIVD ALME VTVY LQSD KDMM VSLY CLDY CCHL RTLK LSVQ R
遺伝子ID:204801
Uniprot:P59045
セルラーロケーション:
計算された分子量:105kDa/111kDa/117kDa
観察された分子量:110kDa
同義語:NLRP11, CLR19.6, NALP11, NOD17, PAN10, PYPAF6, PYPAF7
バックグラウンド:This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms.
UniProt Protein Function:NLRP11: Involved in inflammation (Potential). Belongs to the NLRP family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 19q13.42-q13.43

Molecular Function:RNA binding

NCBI Summary:This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms. [provided by RefSeq, May 2017]
UniProt Code:P59045
NCBI GenInfo Identifier:288558818
NCBI Gene ID:204801
NCBI Accession:P59045.2
UniProt Secondary Accession:P59045,Q2TV85, Q2TV86, Q53ZZ0, Q8NBF5, C9JSF5,
UniProt Related Accession:P59045
Molecular Weight:118kDa
NCBI Full Name:NACHT, LRR and PYD domains-containing protein 11
NCBI Synonym Full Names:NLR family pyrin domain containing 11
NCBI Official Symbol:NLRP11  
NCBI Official Synonym Symbols:NOD17; PAN10; NALP11; PYPAF6; PYPAF7; CLR19.6  
NCBI Protein Information:NACHT, LRR and PYD domains-containing protein 11
UniProt Protein Name:NACHT, LRR and PYD domains-containing protein 11
UniProt Synonym Protein Names:Nucleotide-binding oligomerization domain protein 17; PAAD-and NACHT domain-containing protein 10; PYRIN-containing APAF1-like protein 6
Protein Family:NACHT, LRR and PYD domains-containing protein
UniProt Gene Name:NLRP11  
Anti-NLRP11 Antibody (CAB12132)Western blot analysis of extracts of 293T cells, using NLRP11 antibody (CAB12132) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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